Recombinant Murine Macrophage Inflammatory Protein-3 beta/CCL19 (rMuMIP-3beta/CCL19)

Official Full Name

Recombinant Murine Macrophage Inflammatory Protein-3 beta/CCL19 (rMuMIP-3beta/CCL19)

Synonyms

Beta-chemokine Dxodus-3, CK beta-11, EBI1 Ligand Dhemokine, ELCMacrophage Inflammatory Protein 3 beta

Squence

Squence of Recombinant Murine Macrophage Inflammatory Protein-3 beta/CCL19

Amino Acid Sequence

GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

Synonyms

Beta-chemokine Dxodus-3, CK beta-11, EBI1 Ligand Dhemokine, ELCMacrophage Inflammatory Protein 3 beta

Accession

O70460

Gene ID

24047

Summary

CCL19, also known as EBI1 Ligands chemokine (ELC) and macrophage inflammatory protein-3-beta, is encoded by the CCL19 gene which is located on chromosome 4 in mouse. The protein is expressed at high levels in thymus and lymph nodes, with intermediate levels in trachea and colon and low levels in stomach, lung and some other organs. CCL19 is signal through CCR7 and chemotaxis of T and B lymphocytes and myeloid progenitor cells.

Source

Escherichia coli.

Molecular Weight

Approximately 9.2 kDa, a single non-glycosylated polypeptide chain containing 83 amino acids.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human mature dendritic cells is in a concentration range of 10-100 ng/ml.

Appearance

Sterile filtered white lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.

Endotoxin

Less than 1 EU/ug of rMuMIP-3β/CCL19 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Purity

> 97 % by SDS-PAGE and HPLC analyses.

SDS-PAGE

SDS-PAGE of Recombinant Murine Macrophage Inflammatory Protein-3 beta/CCL19

Pack Size

5ug/100ug/500ug

Safety Data Sheet (SDS) Download

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Technical Data Sheet (TDS) Download

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Links

This product is branded by ChemWhat and sold through our website and here is the corresponding link Recombinant Murine Macrophage Inflammatory Protein-3 beta/CCL19 (rMuMIP-3beta/CCL19) on ChemWhat