Recombinant Murine Interleukin-36 Receptor Antagonist Protein (rMuIL-36RA)

Official Full Name

Recombinant Murine Interleukin-36 Receptor Antagonist Protein (rMuIL-36RA)

Synonyms

IL-1HY1, IL-1 delta, IL-1F5, IL-1H3, IL-1L1

Squence

Squence of Recombinant Murine Interleukin-36 Receptor Antagonist Protein

Amino Acid Sequence

VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAEKVIKGEE ISVVPNRALD ASLSPVILGV QGGSQCLSCG TEKGPILKLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTSPEADQPV RLTQIPEDPA WDAPITDFYF QQCD

Synonyms

IL-1HY1, IL-1 delta, IL-1F5, IL-1H3, IL-1L1

Accession

Q9QYY1

Gene ID

54450

Summary

Source

Escherichia coli.

Molecular Weight

Approximately 16.9 kDa, a single non-glycosylated polypeptide chain containing 154 amino acids.

Biological Activity

Measured by its ability to inhibit IL-36gamma induced IL-6 production by human PBMCs.

Appearance

Sterile filtered white lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4.

Endotoxin

Less than 1 EU/ug of rMuIL-36RA as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.

References

1. Born TL, Smith DE, Garka KE, et al. 2000. J Biol Chem. 275:41528.2. Dunn EF, Gay NJ, Bristow AF, et al. 2003. Biochemistry. 42:10938-44.3. Barton JL, Herbst R, Bosisio D, et al. 2000. Eur J Immunol. 30:3299-308.4. Debets R, Timans JC, Homey B, et al. 2001. J Immunol. 167:1440-6.5. Towne JE, Renshaw BR, Douangpanya J, et al. 2011. J Biol Chem. 286:42594-602.

Purity

> 95 % by SDS-PAGE and HPLC analyses.

SDS-PAGE

SDS-PAGE of Recombinant Murine Interleukin-36 Receptor Antagonist Protein

Pack Size

10ug/100ug/500ug

Safety Data Sheet (SDS) Download

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Technical Data Sheet (TDS) Download

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Links

This product is branded by ChemWhat and sold through our website and here is the corresponding link Recombinant Murine Interleukin-36 Receptor Antagonist Protein (rMuIL-36RA) on ChemWhat