Recombinant Human Cyclophilin D (rHuCyP-D)

Official Full Name

Recombinant Human Cyclophilin D (rHuCyP-D)

Synonyms

PPIF, Cyclophilin F, CyP-M, Rotamase F

Squence

Squence of Recombinant Human Cyclophilin D

Amino Acid Sequence

CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS

Synonyms

PPIF, Cyclophilin F, CyP-M, Rotamase F

Accession

P30405

Gene ID

10105

Summary

CyP-D is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. CyP-D accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. CyP-D is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.

Source

Escherichia coli.

Molecular Weight

Approximately 18.9 kDa, a single non-glycosylated polypeptide chain containing 178 amino acids.

Biological Activity

No data available

Appearance

Sterile colorless liquid.

Formulation

Supplied as a 0.2 um filtered solution in PBS, pH7.4, with 1 mM DTT, 10 % glycerol.

Endotoxin

Less than 0.1 EU/ug of rHuCyP-D as determined by LAL method.

Reconstitution

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 °C as supplied.- 3 months, -20 to -70 °C under sterile conditions after opening.

References

Purity

> 95 % by SDS-PAGE and HPLC analyses.

SDS-PAGE

SDS-PAGE of Recombinant Human Cyclophilin D

Pack Size

10ug/500ug

Safety Data Sheet (SDS) Download

Click to download

Technical Data Sheet (TDS) Download

Click to download

Links

This product is branded by ChemWhat and sold through our website and here is the corresponding link Recombinant Human Cyclophilin D (rHuCyP-D) on ChemWhat