Recombinant Human Cyclophilin D (rHuCyP-D)
Official Full Name
Recombinant Human Cyclophilin D (rHuCyP-D)
Synonyms
PPIF, Cyclophilin F, CyP-M, Rotamase F
Squence
Amino Acid Sequence
CSKGSGDPSS SSSSGNPLVY LDVDANGKPL GRVVLELKAD VVPKTAENFR ALCTGEKGFG YKGSTFHRVI PSFMCQAGDF TNHNGTGGKS IYGSRFPDEN FTLKHVGPGV LSMANAGPNT NGSQFFICTI KTDWLDGKHV VFGHVKEGMD VVKKIESFGS KSGRTSKKIV ITDCGQLS
Synonyms
PPIF, Cyclophilin F, CyP-M, Rotamase F
Accession
Gene ID
Summary
CyP-D is a part of the peptidyl-prolyl cis-trans isomerase (PPIase) family. CyP-D accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. CyP-D is key component of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Source
Escherichia coli.
Molecular Weight
Approximately 18.9 kDa, a single non-glycosylated polypeptide chain containing 178 amino acids.
Biological Activity
No data available
Appearance
Sterile colorless liquid.
Formulation
Supplied as a 0.2 um filtered solution in PBS, pH7.4, with 1 mM DTT, 10 % glycerol.
Endotoxin
Less than 0.1 EU/ug of rHuCyP-D as determined by LAL method.
Reconstitution
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 6 months from date of receipt, -20 to -70 °C as supplied.- 3 months, -20 to -70 °C under sterile conditions after opening.
References
Purity
> 95 % by SDS-PAGE and HPLC analyses.
SDS-PAGE
Pack Size
10ug/500ug
Safety Data Sheet (SDS) Download
Technical Data Sheet (TDS) Download
Links
This product is branded by ChemWhat and sold through our website and here is the corresponding link Recombinant Human Cyclophilin D (rHuCyP-D) on ChemWhat
