Structure of m7GpppNm CAS UENA-0197

m7GpppNm CAS UENA-0197

Identification

CAS Number

UENA-0197

Name

m7GpppNm

Synonyms

cap 1

Properties

Safety Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our m7GpppNm CAS UENA-0197

Application

In the cell, the cap 0 structure is essential for efficient translation of the mRNA that carries the cap. An additional methylation on the 2′O position of the initiating nucleotide generates Cap 1, or refers to as m7GpppNm, where Nm denotes any nucleotide with a 2′O methylation. Cap 1 or m7GpppNm has been shown to be important in evading the cellular innate immune response in vivo. The third generation of cap structure, co-transcriptional capping, capping efficiency 95%

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