Jiangsu Watson Bio Ltd
A ISO 9001 and 14001 certified company, is committed to the development of IVD raw materials including enzymes, carbohydrates, recombinant proteins, and custom biochemicals

IVD RAW Materials

Clinical Chemistry Raw Materials, Molecular Diagnostic Raw Materials, Immunodiagnostic Raw Materials and Coagulation Diagnostic Raw Materials

Custom Reagent

Custom development of the Enzymatic Reagent, Immune Turbidimetric Reagent and Molecular Diagnostic Reagent and provide after-sale service

Glycolipids Science Products

Custom development of Glyco-enzymes, Glyco-amino Acids, Sugar Nucleotides, Glyco-probes, Sugar Intermedias and Glyco-lipids

Watson R&D platform

Jiangsu Watson Bio Ltd, ISO 9001 and 14001 certified, is a research and development company dedicated to the production and supply of high-quality IVD (In vitro diagnostic) raw materials including enzymes, carbohydrates, recombinant proteins and custom biochemicals.

In addition to proteins, Jiangsu Watson is also committed to the upstream key materials and intermediates of new drugs and diagnostic drugs with high technical barriers, difficulty and added value in chemical synthesis. The varieties involve anti-infection, anti-inflammatory, cardiovascular system, Anti-diabetic, anti-tumor, nervous system, gastrointestinal digestive system, chimera drugs (including ADC, PDC, PROTAC, AUTAC, LYTAC) and other fields. The reactions include: protected amino acids and peptides, unnatural amino acids, heterocycle (N,O,S,P) and small molecule scaffold construction, chirality/resolution, coupling, condensation; PEG linker and PEG derivatives series; sulfonation; methylation; halogenation; nitration; catalytic hydrogenation; ring closure, etc.

Jiangsu Watson has established a research and development team of 10 people and operates two production bases covering more than 200 acres. The reactors vary in size from 500L to 5000L and include specialized reaction equipment such as high-temperature (250 degrees), deep cold (-70 degrees), high pressure (100kg), microchannel reaction devices, and photochemical reaction equipment. They also have analytical instruments like HPLC, GC, titration, melting point, specific optical rotation, IR, UV, and moisture analyzers. Among them, the production base located in the Qin Yang Science and Innovation Park of the Henan Province Academy of Sciences has a 600-square-meter laboratory and 42 multifunctional reactors ranging from 1000L to 5000L, with a total reaction volume of 120,000 liters.

As a ChemWhat’s stratigic partner, As a strategic partner of ChemWhat, Watson is also involved in the development and distribution of ChemWhat-branded impurities and other cutting-edge reagents. Utilizing the advantages of the platform and a huge R&D integration capability, we make the development process of new products easy to predict and grasp. At the same time, Watson is fully leveraging the scientific research advantages of many R&D institutions and universities in China, making the scale-up production of complex products easy to control.

Jiangsu Watson not only focuses on biological products but has also participated in the investment of the Watson Chem advanced materials research platform. This platform leads globally in emerging semiconductor fields such as perovskite solar energy, solid electrolyte materials, dopant materials for optical quantum chips, polycrystalline materials, and infrared materials.

Genetic Screening, Cloning & Expression

Watson relies on the R&D platform of institutes and university key labs which have world-class R&D conditions and advanced high-throughput screening, gene cloning and expression technology.

Reagent Customization Service

Strong technical to help customers develop and produce IVD (In vitro diagnostic) reagents in biochemical, immune turbidity, and POCT platform to let customers achieve high efficency.

Optimization & Transformation of Enzyme Molecules

Watson has rich experience in enzyme resource exploration, optimization and transformation. It can explore new enzyme sources from huge enzyme resources and optimize and transform the most suitable enzyme molecules. Through the establishment of extensive and in-depth cooperation with the professional enzyme engineering research teams of many famous universities, Watson can grasp the frontier of enzyme engineering in time and quickly transform into the advanced technology of the company.

Watson can perform important enzyme functions such as enzyme activity, stability, substrate specificity, optimum pH, and organic solvent resistance. By rational design, new enzyme resources with greatly improved performance are quickly obtained to meet the application requirements of the target enzyme in different fields such as diagnosis, medicine, energy, washing and papermaking.

Selection of Molecular Modification of Enzyme

Target enzyme	Transformation nature	Reconstruction effect
Lipase	Thermal stability	Increase 230 times
Glycosyltransferase	Catalytic activity	Increase 380 times
Glucose oxidase	Thermal stability	Increase 120 times
Cellulase	Optimal pH	Reduce 2 pH units
Fructosylpeptide oxidase	Substrate specificity	Selectivity increased 700 times
Esterase	Organic solvent resistance	Tolerance of 80% ethanol
β-lactamase	Stereoselectivity	Increase 200 times

Global Customers

Optimizing Service of Freeze-drying Conditions of Protein

Proteins usually exist in solution after purification, but the storage time of protein solution is very short. A good freeze-drying process can preserve the activity of most proteins, improve the stability of proteins, prolong the storage time, and reduce the freight.

However, protein freeze-drying may cause loss of protein activity, aggregation and other denaturation problems. Watson has been exploring protein freeze-drying process for many years and has accumulated rich freeze-drying experience. It can customize protein freeze-drying process or optimize its original process for customers.

Customer Requirements Definition

Solution Proposal

Contract Signed

Solution Delivery

Follow-up Technical Support

Customer Feedback

Customer Satisfaction